Signal may send cancer’s cellular factories into overdrive
A network of signals active in almost all types of cancer sends the protein factories in our cells into overdrive, and may help fuel a tumour’s uncontrolled growth, new research suggests.
Scientists at The Institute of Cancer Research, one of the world’s most influential cancer research institutes, identified a molecular trigger responsible for ramping up activity of the endoplasmic reticulum (ER) – the cellular factory that makes the building blocks cancer cells need to keep growing.
The findings may help to explain how cancer cells maintain their high levels of metabolism – and could uncover future targets for cancer treatment
The top three images show human hepatocarcinoma cells with the endoplasmic reticulum (blue) and nucleus (red). Copyright: Dr Chris Bakal, The Institute of Cancer Research, London.
The bottom image shows human epithelial cells from breast tissue treated with Torin, an inhibitor of TOR kinase, where the endoplasmic reticulum is (green), nuclei (red) and F-actin (grey) Copyright: Dr Chris Bakal, The Institute of Cancer Research, London.
Exercise caution, especially with things labeled “fresh” pizza
I dunno, I’m most worried about “stairs”
You’re A Rainbow!: Macro Shot Of A Hummingbird’s Face
This is the macro shot of a Green-Crowned Brilliant Hummingbird’s face taken by photographer Chris Morgan while on vacation at the Bosque De Paz biological reserve in Costa Rica. You know, Mother Nature — sometimes you are alright. I mean it’s RARE, but when you do, it almost seems to make up for all the other horrible, horrible shit you do. I’ll tell you what — let’s call a truce this weekend. You promise I won’t find any spiders in my bedroom, and I won’t do anything bad for the environment. “Wait — are you burning car tires?” Haha, I had my fingers crossed you filthy forest nymph!
I was looking up Dr. Seuss drawings for an upcoming project, and I knew he was quite the political cartoonist but didn’t realize how dry the man was. So here, share my pleasant surprise.
Stop using “asexuals are only 1% of the population” as an excuse to dismiss them or try to invalidate people because you know how many people are on this fucking planet? Over seven billion people.
So you know how much “1% of the population” is?? Over seventy million people.
That’s double the size of the entire population of Canada. The entire population of Canada could be asexual.
shhh nobody’s supposed to know